Siddharth Shekar

Graduate Student Armstrong Fellow


Email: sshekar@ee.columbia.edu

M.Tech. (Microelectronics and VLSI Design), Electrical Engineering, IIT Madras, 2013

B.Tech., Electrical Engineering, IIT Madras, 2013

 

My LinkedIn page

My personal webpage

My current research interests lie in the application of integrated circuit (IC) design in non-traditional areas. The integration of electronics and biology typically yields a performance gain not possible with disparate systems.

I am currently working on high-bandwidth solid-state nanopore DNA sequencing platforms. Nanopore based sequencing platforms are among the frontrunners for the third generation of sequencing platforms. One of the biggest issues with nanopore based sequencing, however, is the high translocation rate of DNA through the pore. The aim of this work is to develop high bandwidth low-noise instrumentation amplifiers that are tightly integrated with the pore in order to improve the temporal resolution of nanopore based measurements.

Other Projects

I worked with Sarthak Kalani on the design of a filterless class-D audio amplifier on chip. You can find details about this chip (including a video demonstration!) and the project here.

I have been working on a circuit drawing tool for exporting publication quality graphics. It’s currently in alpha but you can try it out here.

Publications

“Measurement of DNA Translocation Dynamics in a Solid-State Nanopore at 100 ns Temporal Resolution.” Shekar S., Niedzwiecki D., Chien C.-C., Ong P., Fleischer D. A., Lin J., Rosenstein J. K., Drndic M., Shepard K. L., Nano Letters, 2016 (Link)